Scotland international Blair Kinghorn scored 23 points - including two tries - as Toulouse thrashed Exeter to book their place in the Investec Champions Cup semi-finals.
The Scotland fullback crossed twice in the second half, while kicking six conversions and a penalty as the French side, five-times European champions, ran riot after a tight opening 40 minutes.
There was only a single point between the teams at the break; Romain Ntamack and Jack Willis scored the hosts' tries, while Exeter - who did not have Scotland prop Alec Hepburn or injured Jonny Gray in their team, hit back through England flanker Ethan Roots.
The French side took control in the second half as Kinghorn - who moved to Toulouse from Edinburgh in December - scored either side of Pita Ahki's try, before Antoine Dupont and Juan Cruz Mallia also crossed.
Ahki and Mallia added further tries to set up a last four clash with Harlequins, who beat Bordeaux in a thriller on Saturday.
In the other semi-final, Northampton - whose squad includes Scotland's Rory Hutchinson - will travel to Croke Park to face Leinster.
Saints sealed their place with a 59-22 thrashing of the Bulls, who sent a second-string side to Franklin's Gardens, while Leinster knocked out last year's winners La Rochelle with a 40-13 thumping at the Aviva Stadium.
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