Sebastian Cancelliere will make his return from injury for Glasgow Warriors against the Sharks in Durban tomorrow, as Franco Smith makes eight changes from the win over Zebre last weekend.
Up front, Scotland trio Nathan McBeth, Scott Cummings and Matt Fagerson all return, as does hooker Gregor Hiddleston.
Behind the scrum, Cancelliere is back for the first time since the round one defeat to Ulster having overcome a foot injury and replaces fellow countryman Facundo Cordero on the wing.
Sione Tuipulotu also returns and assumes the captaincy as he partners Stafford McDowall in midfield.
Tom Jordan takes over at fly-half from Adam Hastings, who is named on the bench.
There is no place in the matchday 23 for Richie Gray, who will leave the club for Toyota Verblitz next month.
Head coach Smith said: “To play a Sharks side containing 12 Springboks coming off a Rugby Championship win is a daunting task and one that will be a big opportunity for us to measure ourselves against.
“The levels of experience in the Sharks squad are near-unmatched in the URC and is a hallmark of the quality they have available.”
The teams
The Sharks: Aphelele Fassi, Eduan Keyter, Lukhanyo Am, Andre Esterhuizen, Makazole Mapimpi, Jordan Hendrikse, Jaden Hendrikse; Ox Nche, Bongi Mbonambi, Vincent Koch, Eben Etzebeth (captain), Emile van Heerden, Siya Kolisi, Manu Tshituka, Phepsi Buthelezi
Replacements: Fez Mbatha, Trevor Nyakane, Ruan Dreyer, Jason Jenkins, James Venter, Grant Williams, Siya Masuku, Jurenzo Julius
Glasgow Warriors: Josh McKay, Sebastian Cancelliere, Stafford McDowall, Sione Tuipulotu, Kyle Rowe, Tom Jordan, George Horne; Nathan McBeth, Gregor Hiddleston, Zander Fagerson, Max Williamson, Scott Cummings, Matt Fagerson, Rory Darge, Jack Dempsey
Replacements: Johnny Matthews, Rory Sutherland, Sam Talakai, Alex Samuel, Gregor Brown, Henco Venter, Jamie Dobie, Adam Hastings
Glasgow Warriors:
Read the rules here